Fear of Falling in People With Multiple Sclerosis: Which Clinical Characteristics Are Important?

Hanan Khalil1, Alham Al-Shorman2, Khalid El-Salem3

  • 1Department of Rehabilitation Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.

Physical Therapy
|April 27, 2017
PubMed
Abstract

Insights

Fear of falling in multiple sclerosis (MS) patients is linked to motor, cognitive, and sleep issues. Addressing these factors is key for reducing fall risk and improving quality of life.

Area of Science:

  • Neurology
  • Rehabilitation Science
  • Quality of Life Research

Background:

  • Fear of falling (FOF) is a significant predictor of health outcomes and quality of life in multiple sclerosis (MS) patients.
  • Factors contributing to FOF in MS are not extensively studied, necessitating further investigation.

Purpose of the Study:

  • To identify and explore predictors of fear of falling (FOF) in individuals with multiple sclerosis (MS).

Main Methods:

  • Seventy patients with relapsing-remitting MS were assessed using the Fall Efficacy Scale-International (FES-I) for FOF.
  • Motor function (30-second chair stand test, Berg Balance Scale, 10-Meter Walk Test, 6-Minute Walk Test), cognitive status (Montréal Cognitive Assessment, Symbol Digit Modalities Test), and affective factors (depression, fatigue, sleep quality) were evaluated.

Main Results:

  • Fear of falling (FOF) showed significant correlations with all assessed motor and affective measures.
  • Stepwise regression analysis identified Berg Balance Scale (BBS) for motor function, Montréal Cognitive Assessment (MOCA) for cognition, and sleep disorders as significant predictors of FOF.

Conclusions:

  • Fear of falling in MS is multifactorial, influenced by both motor and non-motor impairments.
  • Therapeutic interventions for reducing fall risk in MS should comprehensively target motor function, cognitive abilities, and sleep quality.

Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.2K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.1K
Preparedness and Phobias01:09

Preparedness and Phobias

Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
401
Toxidromes: Clinical Features01:30

Toxidromes: Clinical Features

Toxidromes are specific patterns of symptoms resulting from toxic substance exposure. They help in the identification and treatment of poisoning. The symptoms of each toxidrome group indicate poisoning by a certain class of chemicals or drugs.1. Sympathomimetic: Stimulates the sympathetic nervous system. Symptoms include agitation, increased heart rate (HR), blood pressure (BP), respiratory rate (RR), temperature, and pupil size. Drugs like cocaine and amphetamines, along with tremors and...
51
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
537
Panic Disorder01:27

Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
934