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![Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59557.jpg&w=3840&q=50)
Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941
Published on: April 28, 2019
Evaluation of kinetic programs in various automated perimeters
Shigeki Hashimoto1, Chota Matsumoto2, Mariko Eura2
1Department of Ophthalmology, Faculty of Medicine, Kindai University, Ohnohigashi, Osakasayama City, Osaka, 589-8511, Japan. hasimoto@med.kindai.ac.jp.
Automated perimeters were tested for clinical usefulness in detecting visual field defects. OCTOPUS GKP accurately depicted all simulated patterns, making it the most suitable kinetic perimetry method.
Area of Science:
- Ophthalmology
- Visual Science
Background:
- Kinetic perimetry is crucial for assessing visual field defects.
- Evaluating automated kinetic perimetry programs is essential for clinical application.
Purpose of the Study:
- To compare the clinical usefulness of four automated kinetic perimetry programs.
- To assess their efficacy in detecting various simulated visual field (VF) patterns.
Main Methods:
- Four kinetic programs (Humphrey, OCULUS, OCTOPUS GKP, Kowa) were evaluated.
- Simulated VF patterns included concentric contraction, temporal island, central/temporal islands, and ring scotoma.
- Stimuli varied in size and speed, compared against Goldmann manual kinetic perimetry (MKP).
Main Results:
- OCTOPUS GKP, OCULUS, and Kowa generated isopters comparable to MKP, though influenced by examiner skill.
- Humphrey had target presentation restrictions; OCULUS and Kowa faced isopter drawing/scotoma filling issues.
- OCTOPUS GKP uniquely detected and depicted all four simulated defect patterns accurately.
Conclusions:
- OCTOPUS GKP demonstrated superior performance in assessing kinetic fields with diverse defect patterns.
- It offers accurate detection and depiction, making it the most clinically useful automated kinetic perimetry method.
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