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Related Experiment Video

Updated: Mar 3, 2026

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique
06:11

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique

Published on: May 2, 2025

661

Risk factors for postoperative hypocalcemia.

Giovanni Docimo1, Roberto Ruggiero2, Giuseppina Casalino2

  • 1Department of General Surgery, General and Endocrine Surgical Unit, Second University of Naples, Via Pansini 5, 80131, Naples, Italy. giovanni.docimo@unina2.it.

Updates in Surgery
|April 27, 2017
PubMed
Summary

Hypocalcaemia is a common complication after thyroidectomy. Malignant pathology and central-compartment neck dissection are significant risk factors for developing hypocalcaemia post-surgery.

Keywords:
HypocalcaemiaHypoparathyroidismThyroid surgeryTotal thyroidectomy

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Last Updated: Mar 3, 2026

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique
06:11

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique

Published on: May 2, 2025

661

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Otolaryngology

Background:

  • Hypocalcaemia is a frequent complication following thyroidectomy.
  • Predictive preoperative factors for hypocalcaemia remain unclear.
  • Understanding risk factors is crucial for patient management.

Purpose of the Study:

  • To identify preoperative risk factors for hypocalcaemia after total thyroidectomy (TT).
  • To evaluate the association between clinical, pathological, and surgical details and hypocalcaemia incidence.
  • To inform clinical practice regarding risk stratification and management.

Main Methods:

  • Retrospective analysis of 328 patients undergoing TT between January 2014 and January 2016.
  • Comparison of clinical and pathological characteristics between normocalcemic and hypocalcemic groups.
  • Univariate and multivariate logistic regression analyses to determine risk ratios.

Main Results:

  • Malignant pathology and central-compartment neck dissection (CCND) were significant risk factors for hypocalcaemia.
  • Female gender, presence of ≥2 parathyroid glands in specimens, and operative time >120 min were associated with increased risk on univariate analysis.
  • Malignant pathology and CCND significantly predicted symptomatic and transient hypocalcaemia in multivariate analysis.

Conclusions:

  • Malignant pathology and CCND are significant risk factors for postoperative hypocalcaemia.
  • Close monitoring and prompt therapy are recommended for patients with these risk factors.
  • Further research may elucidate additional predictive markers for thyroidectomy-associated hypocalcaemia.