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Immunopharmacology and immunotoxicity of zinc diethyldithiocarbamate

G Renoux1, M Renoux, J M Guillaumin

  • 1Laboratoire d'Immunologie, Faculté de Médicine, Tours, France.

International Journal of Immunopharmacology
|January 1, 1988
PubMed

Zinc is essential for the functions of the immune system, and sodium diethyldithiocarbamate (imuthiol) restores and regulates the numbers and activities of cells of the T-cell lineage. The combination of both elements was therefore tested for immune enhancement and immunotoxicity. The data presented herein show that the administration of zinc diethyldithiocarbamate was devoid of immunoenhancing influence on the responses to T-cell mitogens, and exerted a cytocidal effect on spleen lymphocytes.

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