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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.1K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

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Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
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Related Experiment Video

Updated: Mar 3, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.6K

Thermal ablation for asthma: current status and technique.

William Krmisky1, Michal J Sobieszczyk2, Saiyad Sarkar1

  • 1Interventional Pulmonary and Critical Care Medicine, MedStar Franklin Square Hospital Center, Baltimore, Maryland, USA.

Journal of Thoracic Disease
|April 28, 2017
PubMed
Summary

Bronchial thermoplasty (BT) offers a safe and effective treatment for severe asthma by reducing airway smooth muscle. This novel radiofrequency wave therapy improves quality of life and decreases exacerbations in patients unresponsive to medication.

Keywords:
Asthmaasthma exacerbationbronchial thermoplasty (BT)pulmonary functionreactive airway disease

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Related Experiment Videos

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Area of Science:

  • Pulmonology
  • Medical Devices
  • Interventional Pulmonology

Background:

  • Severe asthma remains a challenge, often refractory to standard medical therapies.
  • Airway hyperresponsiveness, driven by smooth muscle hypertrophy, is a key feature.
  • Novel therapeutic approaches are needed to manage severe asthma effectively.

Purpose of the Study:

  • To evaluate the efficacy and safety of Bronchial Thermoplasty (BT) for severe asthma.
  • To assess the impact of BT on quality of life and exacerbation rates.
  • To explore BT as a cost-effective option for difficult-to-treat asthma.

Main Methods:

  • Bronchial thermoplasty involves applying radiofrequency energy to segmental bronchi via a catheter.
  • The procedure aims to reduce airway smooth muscle mass.
  • Randomized clinical trials form the basis of the evidence presented.

Main Results:

  • BT demonstrates significant improvements in quality of life for severe asthma patients.
  • A reduction in asthma exacerbation rates is observed post-treatment.
  • The technique is considered safe and cost-effective for refractory asthma.

Conclusions:

  • Bronchial thermoplasty is a viable treatment option for severe asthma unresponsive to medication.
  • Further research is required to elucidate the precise mechanism of action.
  • Identifying specific asthma subphenotypes that benefit most from BT is an area for future study.