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Flow Cytometry

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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Updated: Mar 3, 2026

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

Published on: March 13, 2017

Microfluidics in flow cytometry and related techniques.

¹Hematology Biology, University Hospital, Nantes, France.

International Journal of Laboratory Hematology

|April 28, 2017

Summary

This summary is machine-generated.

Microfluidics technology, while less known than blood analyzers and flow cytometry, offers innovative solutions for hematology. This field, leveraging miniaturization and nanoengineering, is poised to revolutionize hematology diagnostics.

Keywords:

Hematology cdll sorting cell count flow cytometry microfluidics

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Area of Science:

Hematology
Microfluidics
Laboratory Automation

Background:

Laboratory automation has significantly advanced hematology, improving speed and data robustness in blood analysis and flow cytometry.
Microfluidics, a developing field, remains largely confined to academic research but shows growing potential in hematology applications.
Miniaturization in microfluidics draws on advancements in electronics and nanoengineering.

Purpose of the Study:

To provide an overview of the fundamental principles driving microfluidics development.
To present a selection of specific microfluidic applications in hematology.
To highlight the potential of microfluidics to transform the field of hematology.

Main Methods:

Literature search to identify innovative microfluidic solutions for hematology.
Analysis of the physics governing fluid dynamics in microchips.
Review of existing and emerging applications in cell counting, flow cytometry, cell sorting, and ex vivo testing.

Main Results:

Numerous innovative microfluidic techniques have been developed to manage fluid behavior at the microscale.
Applications span various hematological analyses, including cell counting, flow cytometry, and cell sorting.
Microfluidics presents a growing body of research with significant potential for hematology.

Conclusions:

Microfluidics offers a promising avenue for innovation in hematology, building on principles from electronics and nanoengineering.
The technology has the potential to revolutionize hematology diagnostics and research.
Further exploration of microfluidic applications is encouraged for future advancements in the field.