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Updated: Mar 3, 2026
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Serum vascular endothelial growth factor receptor-3 levels in patients with esophageal squamous cell cancer
Aim:
Esophageal cancer is one of the most aggressive tumors of the gastrointestinal tract. In this study, we quantified the serum vascular endothelial growth factor-3 (VEGFR-3) expression in patients with esophageal squamous cell carcinoma (ESCC) to evaluate the role of VEGFR-3 in ESCC.
Materials And Methods:
Ninety five patients with ESCC were studied. Pre-therapy and preoperative samples were stored and ELISA was used to designate the concentrations of VEGFR-3.
Results:
The serum values of VEGFR-3 were significantly higher in patients with ESCC than in healthy donors (p<0.0001).
Conclusions:
The results imply a very good sensitivity of VEGFR-3 in ESCC. VEGFR-3 may be a good diagnostic biomarker for ESCC.
Key Words:
Biomarker, ESCC, VEGFR-3.
