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Updated: Mar 3, 2026
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Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
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Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics
Joohee Kim1, Minji Kim1, Mi-Sun Lee1
1School of Materials Science and Engineering, School of Energy and Chemical Engineering, Wearable Electronics Research Group, Center for Smart Sensor Systems, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
Nature Communications
|April 28, 2017
Summary
This study presents a novel multifunctional contact lens sensor capable of simultaneously monitoring glucose levels and intraocular pressure. This wearable device offers a significant advancement over single-analyte sensors and maintains a clear field of vision.
Area of Science:
- Biomedical Engineering
- Ophthalmology
- Biosensors
Background:
- Wearable contact lenses offer direct physiological parameter monitoring via body fluid biomarkers.
- Existing contact lens sensors typically detect only one analyte and can obstruct vision.
Purpose of the Study:
- To develop a multifunctional contact lens sensor for simultaneous glucose and intraocular pressure monitoring.
- To overcome limitations of single-analyte detection and visual obstruction in previous ocular sensors.
Main Methods:
- Developed a contact lens sensor integrated into an actual ocular contact lens.
- Utilized changes in electrical resistance and capacitance to measure glucose in tears and intraocular pressure.
- Conducted in-vivo and in-vitro tests on rabbit and bovine eyeballs.
Main Results:
- Demonstrated reliable operation of the multifunctional contact lens sensor.
- Successfully achieved simultaneous and independent measurement of tear glucose levels and intraocular pressure.
- Validated the device's performance through comprehensive testing.
Conclusions:
- The developed contact lens sensor enables simultaneous, independent monitoring of glucose and intraocular pressure.
- This innovation advances wearable ocular diagnostics with a non-obstructive, multifunctional design.
