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Anesthetic consideration for neuromuscular diseases
Jeffery A Katz1, Glenn S Murphy
1Northshore University Health System, University of Chicago, Pritzker School of Medicine, Illinois, USA.
Current Opinion in Anaesthesiology
|April 28, 2017
Summary
Perioperative management of patients with neuromuscular disorders requires careful anesthetic drug assessment to prevent postoperative complications. Avoiding succinylcholine and using quantitative monitoring can improve patient outcomes.
Area of Science:
- Anesthesiology
- Neurology
- Critical Care Medicine
Background:
- Patients with neuromuscular disorders face increased risks of postoperative complications.
- Anesthetic drugs administered during surgery can exacerbate these risks.
- Preoperative assessment is crucial for mitigating morbidity and mortality.
Purpose of the Study:
- To review perioperative management strategies for patients with neuromuscular disorders.
- To highlight anesthetic implications and potential complications.
- To examine recent findings on drug safety and monitoring.
Main Methods:
- Literature review of perioperative management in neuromuscular disorders.
- Analysis of anesthetic drug risks and benefits.
- Evaluation of case series and reports on specific agents like sugammadex.
Main Results:
- Succinylcholine use is contraindicated in certain neuromuscular diseases due to severe risks.
- Quantitative neuromuscular monitoring is recommended with nondepolarizing agents.
- Sugammadex shows promise in safely reversing neuromuscular blockade with minimal residual effects.
Conclusions:
- Thorough preoperative assessment and tailored anesthetic management are essential.
- Avoiding specific anesthetic agents and utilizing advanced monitoring can reduce complications.
- Updated management strategies, including newer agents like sugammadex, improve patient safety.
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