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Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
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Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

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An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
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Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
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Endoscopic Procedures V: ERCP01:26

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Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
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Esophageal Varices-II: Clinical Features and Management01:28

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Endoscopic Procedures II: Colonoscopy01:25

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The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
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Related Experiment Video

Updated: Mar 3, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Evidence-Based Guide on Capsule Endoscopy for Small Bowel Bleeding.

Shabana F Pasha1, Jonathan A Leighton1

  • 1Dr Pasha is an associate professor of medicine and Dr Leighton is a professor of medicine in the Division of Gastroenterology and Hepatology at the Mayo Clinic in Scottsdale, Arizona.

Gastroenterology & Hepatology
|April 29, 2017
PubMed
Summary
This summary is machine-generated.

Capsule endoscopy is the primary diagnostic tool for small bowel bleeding, offering higher diagnostic yield for overt bleeding when performed promptly. However, it has limitations in detecting solitary lesions and carries a risk of retention in patients with obstruction.

Keywords:
Capsule endoscopycomputed tomography enterographydeep enteroscopydouble-balloon enteroscopyobscure gastrointestinal bleedingsmall bowel

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Area of Science:

  • Gastroenterology
  • Medical Imaging
  • Diagnostic Procedures

Background:

  • Small bowel bleeding presents diagnostic challenges.
  • Capsule endoscopy has emerged as a key tool for evaluating small bowel pathologies.
  • Understanding its efficacy and limitations is crucial for patient management.

Purpose of the Study:

  • To evaluate the diagnostic yield and clinical utility of capsule endoscopy for small bowel bleeding.
  • To assess the role of capsule endoscopy in conjunction with other imaging modalities.
  • To identify the main adverse events associated with capsule endoscopy.

Main Methods:

  • Systematic review of studies on capsule endoscopy for small bowel bleeding.
  • Analysis of diagnostic yield based on bleeding presentation (overt vs. occult).
  • Comparison of capsule endoscopy findings with cross-sectional imaging and subsequent management.

Main Results:

  • Capsule endoscopy demonstrates higher diagnostic yield in overt small bowel bleeding compared to occult bleeding.
  • Timely performance of capsule endoscopy post-bleeding presentation improves diagnostic yield.
  • Capsule endoscopy is effective for detecting vascular and inflammatory lesions but has a notable miss rate for solitary lesions like tumors.
  • Capsule retention is the primary adverse event, particularly in patients with small bowel obstruction.

Conclusions:

  • Capsule endoscopy is the preferred diagnostic test for overt and occult small bowel bleeding.
  • It plays a complementary role with cross-sectional imaging in guiding patient management.
  • While valuable for certain lesions, its miss rate for solitary tumors necessitates consideration of other diagnostic approaches.