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Updated: Mar 3, 2026

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Scandium-catalysed intermolecular hydroaminoalkylation of olefins with aliphatic tertiary amines
Adi E Nako1, Juzo Oyamada1, Masayoshi Nishiura1
1Organometallic Chemistry Laboratory and RIKEN Center for Sustainable Resource Science , RIKEN , 2-1 Hirosawa, Wako , Saitama , 351-0198 , Japan .
Abstract:
A homoleptic scandium trialkyl complex in combination with a borate compound served as an excellent catalyst for the C-H addition of aliphatic tertiary amines to olefins. This highly regiospecific, 100% atom efficient C-H bond alkylation reaction was applicable to a wide variety of tertiary amines and olefins, including functionalised styrenes and unactivated α-olefins. This work represents the first example of rare-earth catalysed olefin hydroaminoalkylation and also the first example of catalytic C-H addition of aliphatic tertiary amines to olefins with any catalyst.
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