Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

6.4K
GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory...
6.4K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

1.1K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
1.1K
Biasing of P-N Junction01:16

Biasing of P-N Junction

2.2K
The operation of a p-n junction diode involves various biasing conditions, including forward bias, reverse bias, and equilibrium.
In equilibrium, no external voltage is applied across the p-n junction. The depletion region is formed at the junction interface due to the diffusion of carriers, which leaves behind charged dopants, acceptors on the p-side, and donors on the n-side. These immobile charges create an electric field that prevents further diffusion of carriers. The related energy band...
2.2K
Nuclear Overhauser Enhancement (NOE)01:06

Nuclear Overhauser Enhancement (NOE)

1.5K
Irradiation of a spin-active nucleus causes an increase or decrease in the signal intensity of neighboring nuclei that are not necessarily chemically bonded or involved in J-coupling. This phenomenon, called the nuclear Overhauser enhancement (NOE), results from through-space interactions between the nuclear spins. The NOE effect decreases with increasing internuclear distance and is generally not observed beyond 4 angstroms. In NOE, dipole-dipole interactions between neighboring spin-active...
1.5K
Non-gated Ion Channels01:24

Non-gated Ion Channels

8.4K
Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....
8.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lorentzian Switching Dynamics in HZO-Based FeMEMS Synapses for Neuromorphic Weight Storage.

Nano letters·2026
Same author

Comprehensive Characterization of Oligolactide Architecture by Multidimensional Chromatography and Liquid Chromatography-Mass Spectrometry.

ACS omega·2026
Same author

Nanomechanical thermometry for probing sub-nW thermal transport.

Microsystems & nanoengineering·2024
Same author

Cavity-agnostic acoustofluidic manipulations enabled by guided flexural waves on a membrane acoustic waveguide actuator.

Microsystems & nanoengineering·2024
Same author

Quantum Oscillations in Graphene Using Surface Acoustic Wave Resonators.

Physical review letters·2023
Same author

GHz ultrasonic sensor for ionic content with high sensitivity and localization.

iScience·2023

Related Experiment Video

Updated: Mar 3, 2026

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications
11:25

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications

Published on: April 21, 2016

11.7K

An optically-gated AuNP-DNA protonic transistor.

Songming Peng1, Amit Lal, Dan Luo

  • 1Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA. songming@caltech.edu.

Nanoscale
|April 29, 2017
PubMed
Summary
This summary is machine-generated.

This study introduces a novel light-gated protonic transistor using gold nanoparticle-DNA hybrid membranes. This innovation enables remote control of ionic devices, paving the way for advanced biomedical applications.

More Related Videos

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine
10:48

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine

Published on: January 25, 2019

9.8K
Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons
08:20

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

Published on: March 28, 2016

8.4K

Related Experiment Videos

Last Updated: Mar 3, 2026

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications
11:25

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications

Published on: April 21, 2016

11.7K
Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine
10:48

Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine

Published on: January 25, 2019

9.8K
Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons
08:20

Optical Control of a Neuronal Protein Using a Genetically Encoded Unnatural Amino Acid in Neurons

Published on: March 28, 2016

8.4K

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Materials Science

Background:

  • Bio-interface transistors are crucial for merging electronics with biological systems, as ions/protons carry electrical signals in vivo.
  • Existing ionic transistors rely on electrostatic gates, necessitating complex wiring and limiting remote operation.
  • Optical gating has not been previously explored for ionic devices, despite its potential for remote control and wavelength selectivity.

Purpose of the Study:

  • To develop and demonstrate a novel light-gated protonic transistor.
  • To investigate the potential of optical control for ionic devices, overcoming limitations of electrostatic gating.
  • To explore the use of gold nanoparticle-DNA hybrid membranes in transistor fabrication.

Main Methods:

  • Fabrication of a light-gated protonic transistor using a gold nanoparticle and DNA (AuNP-DNA) hybrid membrane.
  • Utilizing light as an external stimulus to control the transistor's on/off states.
  • Characterizing the device performance, including on/off current ratio and wavelength selectivity.

Main Results:

  • The AuNP-DNA transistor demonstrated complete light-induced switching (on/off).
  • Achieved a high on/off current ratio of up to 2 orders of magnitude.
  • Exhibited wavelength selectivity due to the plasmonic effect of gold nanoparticles, enabling specific light responses.

Conclusions:

  • The developed light-gated protonic transistor offers a promising alternative to traditional ionic transistors.
  • The device's remote control and wavelength selectivity capabilities open new possibilities for ionic circuits and biomedical applications.
  • This work highlights the potential of hybrid nanomaterials for advanced electronic and bioelectronic interfaces.