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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Tool-supported Interactive Correction and Semantic Annotation of Narrative Clinical Reports
Karel Zvára, Marie Tomečková, Jan Peleška
1Prof. Jana Zvárová, Ph.D., DSc., FEFMI, Institute of Hygiene and Epidemiology, 1st Faculty of Medicine, Charles University, Studnickova 7, 128 00 Prague 2, Czech Republic,
This study introduces a three-phase method and software for processing Czech clinical reports. The approach enables easier data extraction and annotation for improved electronic health record utilization and medical research.
Area of Science:
- Medical Informatics
- Natural Language Processing
- Clinical Data Management
Background:
- Narrative clinical reports in electronic health records require structured processing for secondary use.
- Physicians and automated systems benefit from easier, less erroneous data interpretation.
- Challenges exist in extracting structured information from narrative text, especially in less-resourced languages.
Purpose of the Study:
- To design a method and software for interactive correction and semantic annotation of narrative clinical reports.
- To facilitate easier and less erroneous processing of clinical reports by unfamiliar physicians and decision-support systems.
- To gain insights into clinical report creation and annotation processes, and to provide a ground-truth dataset for automated transformation training.
Main Methods:
- A three-phase preprocessing method: tokenization, normalization, and enrichment with extracted structured information.
- Development of software tools for interactive correction, expansion, and semantic annotation of narrative clinical reports.
- Validation of the method in the cardiology domain using Czech narrative clinical reports.
Main Results:
- The three-phase preprocessing method was validated on 49 Czech narrative clinical reports in cardiology.
- Two cardiologists annotated 1500 clinical terms, linking them to classification systems (ICD 10, SNOMED CT, LOINC, LEKY).
- A database of correct clinical terms and codebook terms was established.
Conclusions:
- Structured information was successfully extracted from Czech narrative clinical reports using the proposed method.
- The developed software, tailored for Czech, can serve as a model for adapting the approach to other less-resourced languages.
- Extracted structured information supports medical decision-making, quality assurance, and further research.
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