Related Experiment Video
Updated: Mar 3, 2026

10:14
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
4.3K
Focal choroidal excavation-morphological features and clinical correlation
C Y Chung1,2,3, S H Li1,2,3, K K W Li1,2,3
1Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.
Eye (London, England)
|April 29, 2017
Summary
Focal choroidal excavation (FCE) often presents unilaterally and can be associated with macular pathologies like polypoidal choroidal vasculopathy (PCV). Angiography is recommended for both eyes, even in asymptomatic cases, to assess potential risks.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Focal choroidal excavation (FCE) is a recognized morphological finding in the choroid.
- Understanding its clinical significance and associations is crucial for patient management.
Purpose of the Study:
- To detail the morphological and clinical characteristics of FCE.
- To investigate correlations between FCE features and concurrent macular pathologies.
Main Methods:
- Retrospective case series analysis of optical coherence tomography (OCT) scans.
- Inclusion of 16 patients diagnosed with FCE over a defined period.
- Statistical analysis to determine significance (P<0.05).
Main Results:
- All 16 FCE cases were unilateral, with a mean age of diagnosis of 52.56 years.
- Mean FCE greatest linear dimension (GLD) was 636.25 μm; mean choroidal thickness was 183.63 μm.
- Concurrent macular pathology was observed in 25% of FCE eyes and 31.3% of fellow eyes, including polypoidal choroidal vasculopathy (PCV).
Conclusions:
- A significant association exists between FCE and macular pathologies in either the involved or fellow eye.
- Angiography for both eyes is advised, even for asymptomatic FCE, for comprehensive risk assessment.
- FCE greatest linear dimension (GLD) may aid in clinical risk stratification.

