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Percutaneous revascularization in patients treated with thoracic radiation for cancer
Erin A Fender1, Jackson J Liang2, Terence T Sio3
1Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Objectives:
To assess coronary revascularization outcomes in patients with previous thoracic radiation therapy (XRT).
Background:
Previous chest radiation has been reported to adversely affect long term survival in patients with coronary disease treated with percutaneous coronary interventions (PCI).
Methods:
Retrospective, single center cohort study of patients previously treated with thoracic radiation and PCI. Patients were propensity matched against control patients without radiation undergoing revascularization during the same time period.
Results:
We identified 116 patients with radiation followed by PCI (XRT-PCI group) and 408 controls. Acute procedural complications were similar between groups. There were no differences in all-cause and cardiac mortality between groups (all-cause mortality HR 1.31, P=.078; cardiac mortality 0.78, P=.49).
Conclusion:
Patients with prior thoracic radiation and coronary disease treated with PCI have similar procedural complications and long term mortality when compared to control subjects.
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