Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

10.1K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
10.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ambiol Prevents Changes in the Functional Characteristics of Mitochondria Under Hypoxia.

International journal of molecular sciences·2026
Same author

Photooxidation Dynamics of Lipofuscin in the Presence of Carotenoid-Binding Protein AstaP: Fluorescence Lifetime Imaging and Pigment Composition Analysis.

The journal of physical chemistry. B·2026
Same author

Biomarkers of Progressive Chronic Heart Failure: The Results of Blood Proteomic Analysis.

Kardiologiia·2026
Same author

Redox Modulation in Therapy of Cancer: Some Pros and Cons.

Antioxidants (Basel, Switzerland)·2025
Same author

Ploidy and Implantation Potential: Non-Invasive Small Non-Coding RNA-Based Health Assessment of Day 5 and 6 Blastocysts.

International journal of molecular sciences·2025
Same author

Antibody-Dependent Cytotoxicity of Monocytes in Preeclampsia Is Associated with Soluble Forms of HLA.

International journal of molecular sciences·2025

Related Experiment Video

Updated: Mar 3, 2026

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
09:35

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Published on: January 29, 2020

8.3K

Lutein and its oxidized forms in eye structures throughout prenatal human development.

Ina G Panova1, Marina A Yakovleva2, Alexander S Tatikolov2

  • 1Koltsov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow 119334, Russia.

Experimental Eye Research
|April 30, 2017
PubMed
Summary

This study found lutein and its oxidized forms in the developing human eye tissues, but not zeaxanthin. Lutein presence in the vitreous is temporary during prenatal development.

Keywords:
Ciliary body and iris with stromaHuman fetal eyeLensLuteinLutein oxidized formsRetinaRetinal pigment epithelium with choroidVitreous

More Related Videos

Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
05:03

Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling

Published on: December 27, 2024

1.8K
Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells
10:02

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells

Published on: December 12, 2014

13.0K

Related Experiment Videos

Last Updated: Mar 3, 2026

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
09:35

Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer

Published on: January 29, 2020

8.3K
Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling
05:03

Author Spotlight: Investigating Physiological Functions of Vitamin A Transporters Using HPLC-Based Vitamin A Profiling

Published on: December 27, 2024

1.8K
Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells
10:02

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells

Published on: December 12, 2014

13.0K

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Nutritional Science

Background:

  • Carotenoids, like lutein, are crucial antioxidants.
  • Their presence and role during human eye development are not fully understood.
  • Understanding carotenoid distribution can inform eye health strategies.

Purpose of the Study:

  • To investigate the presence and distribution of carotenoids in human eye tissues during the second trimester of prenatal development.
  • To identify specific carotenoids and their locations within the developing eye.
  • To discuss the potential antioxidant roles of these carotenoids.

Main Methods:

  • Analysis of carotenoid presence in ocular tissues (vitreous body, retina, RPE, CBI, lens).
  • Utilizing techniques to detect lutein, its oxidized forms, and zeaxanthin.
  • Correlating findings with gestational age during the second trimester.

Main Results:

  • Lutein and its oxidized forms were detected in the vitreous body, retina, and retinal pigment epithelium (RPE).
  • Zeaxanthin was not found in any studied ocular tissues.
  • Lutein was transient in the vitreous (absent after 28 weeks gestation); only oxidized forms were found in the lens and ciliary body/iris/choroidal stroma (CBI).

Conclusions:

  • Lutein and its derivatives are present in key ocular tissues during human prenatal development.
  • The distribution and transient nature of lutein suggest specific developmental roles.
  • Further research into the antioxidant functions of carotenoids during eye development is warranted.