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Accessory Structures of the Eye01:17

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Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
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Pseudoexfoliation: An Ocular Finding with Possible Systemic Implications.

Uri Aviv1, Daniel Ben Ner1, Nardeen Sharif1

  • 1Department of Ophthalmology, Wolfson Medical Center, Holon, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The Israel Medical Association Journal : IMAJ
|May 1, 2017
PubMed
Summary
This summary is machine-generated.

Pseudoexfoliation syndrome (PES), an age-related eye condition, involves abnormal protein deposits. These deposits are linked to systemic health issues, including vascular and cognitive risks, warranting further investigation.

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Area of Science:

  • Ophthalmology
  • Systemic Pathology
  • Geriatrics

Background:

  • Pseudoexfoliation syndrome (PES) is a prevalent, age-related disorder affecting millions globally.
  • Characterized by abnormal fibrillar material deposition in the anterior eye segment.
  • Exfoliated fibrils are also found systemically in organs like the skin, heart, lungs, liver, and kidneys.

Purpose of the Study:

  • To review current literature on the systemic implications of Pseudoexfoliation Syndrome.
  • To highlight associations between PES and various systemic conditions.
  • To encourage further research into this significant clinical entity.

Main Methods:

  • Comprehensive literature review of recent studies.
  • Analysis of research linking Pseudoexfoliation Syndrome to systemic conditions.
  • Synthesis of findings on the systemic distribution of exfoliated material.

Main Results:

  • Numerous studies associate Pseudoexfoliation Syndrome with increased vascular risk.
  • PES is linked to an elevated risk of dementia.
  • An inflammatory state is frequently observed in patients with Pseudoexfoliation Syndrome.

Conclusions:

  • Pseudoexfoliation Syndrome has significant, widespread systemic implications beyond the eye.
  • The systemic nature of PES suggests a potential role in various age-related diseases.
  • Further research is crucial to understand and manage the systemic effects of Pseudoexfoliation Syndrome.