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Drug Therapy in Adult Congenital Heart Disease

Tahmeed Contractor1, Vadim Levin2, Ravi Mandapati1

  • 1Department of Cardiology, Arrhythmia Center, Loma Linda University International Heart Institute, 11234 Anderson Street, Loma Linda, CA 92354, USA.

Cardiac Electrophysiology Clinics
|May 2, 2017
PubMed

Insights

Adults with congenital heart disease face risks of arrhythmias. This article reviews antiarrhythmic drug use when catheter ablation fails, offering practical guidance for clinicians.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Adult Congenital Heart Disease

Background:

  • Adults with congenital heart disease (ACHD) have a high risk of atrial and ventricular arrhythmias.
  • These arrhythmias increase morbidity and mortality in the ACHD population.
  • Catheter ablation may not always be feasible or effective for arrhythmia management.

Purpose of the Study:

  • To provide a practical overview of antiarrhythmic drug therapy in adults with congenital heart disease.
  • To address the limited existing data on antiarrhythmic use in this specific patient group.
  • To offer clinical guidance and reference materials for healthcare providers.

Main Methods:

  • Literature review on antiarrhythmic drug efficacy and safety in ACHD.
  • Synthesis of current guidelines and expert opinion.
  • Development of practical tables for clinical decision-making.

Main Results:

  • Antiarrhythmic drugs are crucial when catheter ablation is not an option or has failed.
  • Specific considerations for antiarrhythmic use in ACHD patients are highlighted.
  • Reference tables are provided for practical application in daily practice.

Conclusions:

  • Effective management of arrhythmias in ACHD requires careful consideration of antiarrhythmic therapy.
  • This review aims to support clinicians in optimizing antiarrhythmic drug selection and use.
  • Further research is needed to expand the evidence base for antiarrhythmics in ACHD.

Keywords:
AnticoagulationArrhythmiaCongenital heart diseaseDrug therapy

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