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Updated: Mar 3, 2026

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
Published on: January 7, 2014
TMEM230 in Parkinson's disease
Laura Ibanez1, Umber Dube2, John Budde1
1Department of Psychiatry, School of Medicine, Washington University in Saint Louis, Saint Louis, MO, USA.
Abstract:
A study on familial Parkinson disease (PD) described 4 variants in the gene TMEM230 (Chr. 20p13) as the cause of PD. The aim of this study was to test if variants in the TMEM230 gene are associated with PD in 2 independent American European data sets. No variants in the TMEM230 region were found associated with PD, age at onset, or cerebrospinal fluid α-synuclein levels.
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