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Published on: September 5, 2011
Hematological disorders at birth in complicated monochorionic twins
Lianne Verbeek1, Femke Slaghekke2, Marieke Sueters2
1a Division of Neonatology, Department of Pediatrics , Leiden University Medical Center , Leiden , The Netherlands.
Monochorionic twins face risks like twin-twin transfusion syndrome (TTTS) and twin anemia-polycythemia sequence (TAPS). Prompt diagnosis and management of neonatal hematological complications at birth are crucial for better outcomes.
Area of Science:
- Neonatal Medicine
- Perinatology
- Hematology
Background:
- Monochorionic twins are susceptible to severe complications such as twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence (TAPS), and acute peripartum TTTS.
- These conditions arise from inter-twin blood transfusion via placental vascular anastomoses.
Purpose of the Study:
- To review the incidence, management, and outcomes of neonatal hematological complications at birth in TTTS, TAPS, and acute peripartum TTTS.
- To highlight the importance of recognizing and managing these hematological disorders in monochorionic twins.
Main Methods:
- This is a review article, synthesizing existing literature on the topic.
- Focus is on the neonatal period and hematological aspects at birth.
Main Results:
- Hematological disorders, including anemia, polycythemia, and thrombocytopenia, are frequently observed at birth in affected monochorionic twins.
- These disorders can be acute or chronic.
Conclusions:
- Routine measurement of complete blood counts is strongly recommended for all complicated monochorionic twins.
- Increased awareness and appropriate diagnostic testing are essential for prompt and effective management of neonatal hematological complications.
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