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Acute nonlymphocytic leukemia following lung cancer in a patient with a constitutional supernumerary chromosome
M Minamihisamatsu1, J S Gregorio, Y Onozawa
1Division of Radiation Hazards, National Institute of Radiological Sciences, Chiba, Japan.
Cancer Genetics and Cytogenetics
|October 15, 1988
Abstract:
A patient with a constitutional bisatellited supernumerary marker chromosome developed a large cell lung carcinoma and subsequent acute nonlymphocytic leukemia (ANLL) of the M2 type showing an (8;21) translocation and del(9). The ANLL-M2 appeared to be independent of the lung carcinoma. The presence of the supernumerary chromosome might have been associated with the development of the two diseases.