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[3H]imipramine binding sites are decreased in platelets of chronic pain patients
G Magni1, F Andreoli, C Arduino
1Department of Psychiatry, University of Padua School of Medicine, Italy.
Clinical Neuropharmacology
|April 1, 1987
Abstract:
Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients not suffering from major depression and in a control group. Maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different.