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Quantification of propionic acid from Scutellaria baicalensis roots
Eunjung Son1,2, Ho Kyoung Kim1, Hyun Sik Kim3
1KM Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Korea.
Integrative Medicine Research
|May 3, 2017
Summary
Propionic acid, a common preservative, was detected in 94% of Scutellaria baicalensis roots. This study developed a reliable method to quantify propionic acid in this medicinal plant.
Area of Science:
- Phytochemistry
- Analytical Chemistry
Background:
- Propionic acid is a prevalent synthetic preservative.
- Its presence in natural products often indicates antimicrobial additive use.
Purpose of the Study:
- To investigate the presence and quantify propionic acid in Scutellaria baicalensis roots.
- To develop and validate a robust analytical method for propionic acid determination.
Main Methods:
- Development and validation of an ultra-performance liquid chromatography (UPLC) method.
- Quantification of propionic acid in Scutellaria baicalensis root samples from South Korea and China.
Main Results:
- Propionic acid was detected in 94.0% of analyzed Scutellaria baicalensis root samples.
- Average concentrations were 0.41 ± 0.24 mg/g in China samples and 0.76 ± 0.28 mg/g in South Korea samples.
Conclusions:
- This research is the first to report the natural occurrence of propionic acid in Scutellaria baicalensis roots.
- A validated UPLC method provides a reliable tool for propionic acid quantification in this plant species.
Keywords:
Scutellaria baicalensisgeographical differencespropionic acidquantification analysisvalidation
