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Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays
Johan Fenneteau1, Dany Chauvin, Andrew D Griffiths
1Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI), UMR 8231, ESPCI Paris/CNRS, PSL Research University, 10 rue Vauquelin, 75231-Paris Cedex 05, France. janine.cossy@espci.fr.
Chemical Communications (Cambridge, England)
|May 3, 2017
Abstract:
Here we report the conception, synthesis and evaluation of new hydrophilic rhodamine-based enzymatic substrates for detection of peptidase activity compatible with high-throughput screening using droplet-based microfluidics.
