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Na+,K+-ATPase: tissue-specific expression of genes coding for alpha-subunit in diverse human tissues
E D Sverdlov1, N S Akopyanz, K E Petrukhin
1Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, Moscow.
FEBS Letters
|October 24, 1988
Abstract:
The expression of genes coding for alpha and alpha III isoforms of Na+,K+-ATPase alpha-subunit has been studied in human kidney, brain, thyroid and liver cells. The expression was shown to be subjected to a tissue-specific control and also depended on the developmental stage. The tissue-specific expression of genes coding for different isoforms of the catalytic subunit of Na+,K+-ATPase perhaps may be attributed to various functions of proteins belonging to this family.