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Updated: Mar 3, 2026
Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
Published on: August 1, 2025
Preliminary Evidence on Cannabis Effectiveness and Tolerability for Adults With Tourette Syndrome
Elia Abi-Jaoude1, Lei Chen1, Patrina Cheung1
1From the Department of Psychiatry, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada (EA-J); the Department of Psychiatry, University Health Network, University of Toronto, Toronto, Ontario, Canada (EA-J, PS); Global Medicines Development, AstraZeneca Canada, Inc., Mississauga, Ontario, Canada (LC); the Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada (PC); the Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada (TB); and Youthdale Treatment Centers, Toronto, Ontario, Canada (PS).
Abstract:
The authors retrospectively evaluated effectiveness and tolerability of cannabis in 19 adults with Tourette syndrome. Tics scores decreased by 60%, and 18 of the 19 participants were at least "much improved." Cannabis was generally well tolerated, although most participants reported side effects.
