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Right Ventricular Changes in Highly Trained Athletes: Between Physiology and Pathophysiology.
Antonello D'Andrea1, Alberto Morello1, Agostino Mattera Iacono1
1Department of Cardiology, Integrated Diagnostic Cardiology, AORN dei Colli, Second University of Naples, Naples, Italy.
Endurance athletes may develop right ventricular remodeling due to exercise, potentially leading to arrhythmias. Detraining may not fully reverse these changes, suggesting exercise-induced cardiomyopathy.
Area of Science:
- Cardiology
- Sports Medicine
- Exercise Physiology
Background:
- Exercise induces adaptive cardiac remodeling.
- Highly trained endurance athletes experience disproportionate right ventricular (RV) load during exercise.
- This RV load may promote chronic, pro-arrhythmic RV remodeling.
Purpose of the Study:
- To review current knowledge on right heart changes in highly trained athletes.
- To explore how these changes influence cardiac function.
- To discuss the concept of exercise-induced cardiomyopathy.
Main Methods:
- Literature review of studies on cardiac remodeling in athletes.
- Analysis of research on right ventricular adaptation and dysfunction.
- Synthesis of evidence regarding exercise-induced cardiomyopathy.
Main Results:
- Incomplete recovery of RV changes after detraining has been observed.
- Evidence suggests acute myocardial injury and chronic myocardial scarring in some athletes.
- An increased prevalence of arrhythmias supports the existence of exercise-induced cardiomyopathy.
Conclusions:
- Pro-arrhythmic RV remodeling may occur in response to chronic exercise in athletes.
- Exercise-induced cardiomyopathy is a potential consequence of intense endurance training.
- Further research is needed to fully understand RV adaptation and its long-term implications.
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