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Comparison of Carotid Intima-media Thickness in Hypertensive Patients and Control Group
Ghodratollah Naseh1, Mahyar Mohammadi Fard2, Toba Kazemi3
1Department of Surgery, Birjand University of Medical Sciences, Birjand, Iran.
Insights
Hypertensive patients show increased carotid intima-media thickness compared to healthy individuals. Longer hypertension duration may accelerate atherosclerosis, highlighting the need for early intervention.
Area of Science:
- Cardiovascular Medicine
- Diagnostic Imaging
- Public Health
Background:
- Hypertension (HTN) is a prevalent global health issue.
- Despite advances, HTN-related mortality and morbidity remain high.
- Vascular wall changes, assessed via intima-media thickness, are critical HTN complications.
Purpose of the Study:
- To compare Carotid Intima Media Thickness (CIMT) between hypertensive patients and a control group.
- To investigate the relationship between hypertension duration and CIMT.
Main Methods:
- A case-control study involving 43 hypertensive patients and 43 healthy controls.
- Carotid intima-media thickness (IMT) and outer vessel diameter measured by ultrasonography.
- Hypertension was managed with medication in the patient group.
Main Results:
- Mean CIMT was significantly higher in hypertensive patients across all carotid arteries (P < 0.05).
- No significant correlation between hypertension duration and mean CIMT, except in the right internal carotid artery (P = 0.024).
Conclusions:
- Elevated mean CIMT is confirmed in hypertensive individuals compared to controls.
- Hypertension duration may influence the acceleration of atherosclerosis.
Background:
Hypertension (HTN), probably, is the most common public health problem among developed countries. Rapid diagnosis and effective treatment of HTN have not truly stopped the rapid rate of mortality and morbidity caused by HTN. Vascular wall changes are one of the most important and mortal complications of HTN. Ultrasonography was used for the evaluation of this vessel wall disorder by assessing the thickness of the intima and media layer.
Objective:
The objective of this study was to compare the Carotid intima Media Thickness (CIMT) in hypertensive patients and the control group.
Methods:
In a case-control study, 43 patients with documented primary HTN and 43 healthy subjects were assessed as control. Their HTN was controlled by the administration of drugs. The mean age was 53.9 years. The intima-media thickness (IMT) of internal and common carotid and outer vessel diameter were assessed by one radiologist.
Results:
CAIMT in all carotid arteries in the case group was more than that of the controls (P < 0.05). It was found that there was no difference between the length of having HTN and mean CAIMT in the hypertensive, except the right internal carotid (P = 0.024).
Conclusion:
The present study found that the mean CAIMT of all carotid arteries in HTN was more than that of the controls. Moreover, the duration of the HTN can accelerate the atherosclerosis process in hypertensive patients.
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