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Myopericarditis in a patient with hepatitis C and cryoglobulinemic renal disease
Mohamoud A Ali1, Waqas Z Kayani2, Bradley M Linzie3
1Department of Medicine Hennepin County Medical Center Minneapolis Minnesota USA.
Insights
Hepatitis C (HC) can cause cryoglobulinemia, leading to rare but life-threatening myopericarditis and pericardial effusion. This condition, even without a liver transplant, signals severe multiorgan disease.
Area of Science:
- Cardiology
- Hepatology
- Immunology
Background:
- Cryoglobulinemia is a known complication of Hepatitis C (HC).
- Myopericarditis and pericardial effusion are rare manifestations of cryoglobulinemia.
- Liver transplant status is a key factor in presentation.
Abstract:
Although cryoglobulinemia is a well-appreciated complication of hepatitis C (HC), myopericarditis with resulting pericardial effusion is extremely rare, especially in the absence of a liver transplant. In patients with HC, pericardial effusion with impending tamponade can be a florid and potentially life-threatening manifestation of multiorgan cryoglobulinemic disease.
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