Related Experiment Video For DNA methylation
Updated: Mar 3, 2026

Methyl-binding DNA capture Sequencing for Patient Tissues
Published on: October 31, 2016
Epigenetics in endometrial carcinogenesis - part 1: DNA methylation
Carla Bartosch1,2,3,4, José Manuel Lopes3,5,6,7, Carmen Jerónimo2,4,8
1Department of Pathology, Portuguese Oncology Institute of Porto (IPO-Porto), Porto, Portugal.
Abstract:
Carcinogenesis is a multistep multifactorial process that involves the accumulation of genetic and epigenetic alterations. In the past two decades, there has been an exponential growth of knowledge establishing the importance of epigenetic changes in cancer. Our work focused on reviewing the main role of epigenetics in the pathogenesis of endometrial carcinoma, highlighting the reported results concerning each epigenetic mechanistic layer. The present review is the first part of this work, in which we examined the contribution of DNA methylation alterations for endometrial carcinogenesis.
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