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Oral versus intravenous hypertonic saline for exercise-associated hyponatraemia
1University of Sydney, Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Journal of Paediatrics and Child Health
|May 5, 2017
Summary
Oral or intravenous hypertonic saline may treat exercise-associated hyponatraemia. A literature review found limited evidence, with one study suggesting intravenous saline offers better subjective relief and plasma volume expansion compared to oral solutions.
Area of Science:
- Sports Medicine
- Emergency Medicine
- Clinical Nutrition
Background:
- Exercise-associated hyponatraemia (EAH) is a serious condition.
- Current treatment involves intravenous (IV) hypertonic saline, posing challenges.
- Oral therapy is a potential alternative requiring investigation.
Purpose of the Study:
- To review literature on oral versus IV hypertonic saline for EAH in pediatric populations.
- To assess the efficacy and safety of different administration routes for EAH treatment.
Main Methods:
- A comprehensive literature review was conducted.
- Searched for studies comparing oral and IV hypertonic saline for EAH.
- Focused on pediatric populations, but identified a relevant adult study.
Main Results:
- Only one study directly addressed the research question, focusing on adult runners.
- Both oral and IV hypertonic saline showed similar biochemical effects.
- IV hypertonic saline demonstrated superior subjective relief and plasma volume restoration.
Conclusions:
- Evidence for oral hypertonic saline in pediatric EAH is limited.
- Further research is needed to establish optimal treatment guidelines for children.
- IV hypertonic saline remains the standard for acute EAH management.
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