Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Multimodal PET Defines a 'Goldilocks' Thermal Window for Focused Ultrasound Ablation and Immunotherapy Combinations.

bioRxiv : the preprint server for biology·2026

Same author

HMEC-1 extracellular vesicles as regulators of endothelial cell activation under inflammation.

bioRxiv : the preprint server for biology·2026

Same author

Cellularized hydrogel-interfaced cantilever (CHIC) biosensors for monitoring 3D cell culture mechanical properties.

Biosensors & bioelectronics·2026

Same author

Transcriptional analyses identify pericyte-centered signaling programs altered by sex and brain region in Alzheimer's Disease.

Communications biology·2026

Same author

An agent-based model suggests how senescent cell behavior and matrix mechanics drive pulmonary fibrosis in aged mice.

bioRxiv : the preprint server for biology·2026

Same author

Agent-Based Modeling of Idiopathic Lung Fibrosis and Mechanistic Treatments.

bioRxiv : the preprint server for biology·2026

Search research articles

Related Experiment Video

Updated: Mar 3, 2026

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

Published on: June 22, 2012

Microfluidics Technologies and Approaches for Studying the Microcirculation.

Walter L Murfee¹, Shayn M Peirce²

¹Department of Biomedical Engineering, Tulane University, New Orleans, LA, USA.

Microcirculation (New York, N.Y. : 1994)

|May 5, 2017

Summary

This summary is machine-generated.

Microfluidic devices offer advanced ex vivo models for studying microvascular networks, overcoming limitations of traditional experimental platforms. These innovative tools enable deeper understanding of microvascular function and preclinical therapeutic evaluation.

Keywords:

microcirculation microfluidics

More Related Videos

Development of New Therapeutic Applications Using Microfluidics

Development of New Therapeutic Applications Using Microfluidics

Published on: October 1, 2007

Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip

Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip

Published on: October 21, 2013

Related Experiment Videos

Last Updated: Mar 3, 2026

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

Endothelialized Microfluidics for Studying Microvascular Interactions in Hematologic Diseases

Published on: June 22, 2012

Development of New Therapeutic Applications Using Microfluidics

Development of New Therapeutic Applications Using Microfluidics

Published on: October 1, 2007

Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip

Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip

Published on: October 21, 2013

Area of Science:

Biomedical Engineering
Physiology
Microfluidics

Background:

Current ex vivo experimental platforms lack the complexity of in vivo microcirculation.
Developing physiologically relevant models is crucial for microvascular research.

Discussion:

Microfluidics enables recapitulation of microvascular network architecture and hemodynamics.
This technology facilitates study of biochemical and biomechanical mechanisms in microvessels.

Key Insights:

Microfluidics bridges the gap between in vivo and in vitro research models.
Applications include studying angiogenesis, blood cell rheology, and preclinical drug testing.
These platforms enhance understanding of microvascular function and adaptation.

Outlook:

Continued development of microfluidic platforms will advance microvascular research.
Potential for improved preclinical evaluation of therapies targeting the microcirculation.