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Challenges for the pharmaceutical technical development of protein coformulations

Claudia Mueller1, Ulrike Altenburger1, Silke Mohl1

  • 1Late-Stage Pharmaceutical and Process Development, Pharmaceutical Development and Supplies, PTD Biologics Europe (PTDE-P), F. Hoffmann-La Roche Ltd., Basel, Switzerland.

The Journal of Pharmacy and Pharmacology
|May 5, 2017
PubMed
Summary

Developing protein coformulations presents unique challenges in stability, manufacturing, and analytics. Careful consideration throughout the pharmaceutical development process is crucial for creating safe and effective combination protein drug products.

Keywords:
dosage form design and characterizationpharmaceutical analysispharmaceutics and drug delivery

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