[Acute mesenteric ischemia: the importance of early diagnosis and aggressive revascularization]

Despite the advances in diagnostic and therapeutic approaches, acute mesenteric ischemia (AMI) remains associated with a dismal prognosis. The goal of this study was to review and report our department's experience in the surgical treatment of AMI and to identify predictive factors of postoperative morbidity and mortality.

We performed a retrospective analysis of the patients that underwent surgical revascularization after embolic or thrombotic AMI, between January 2008 and December 2015. Patient's comorbidities/cardiovascular risk factors, chosen diagnostic and therapeutic strategies, and postoperative complications were studied.

Fifteen patients (66.7% female) were treated, with a mean age of 68.6±16.3 years (41-88). The most common cause of AMI was embolism (n=9; 60%). The most prevalent cardiovascular risk factor was hypertension (86.7%). All patients complained of abdominal pain, and in 66.7% of cases leukocytosis and elevated lactate dehydrogenase levels were observed. All patients were studied with abdomino-pelvic CT angiography. The mean ischemic time was 27.9±29.5 hours (3-96 hours). Midline laparotomy was performed in 14 patients [thromboendarterectomy of the superior mesenteric artery (SMA) (n=1; 6.7%); embolectomy of the SMA (n=8; 53.3%); mesenteric bypass (n=3; 20%); retrograde PTA and stenting of the SMA (n=2; 13.3%)]. One patient (6.7%) underwent thromboaspiration and catheter fibrinolysis. Four patients required enterectomy (26.7%). Second-look surgery was performed in 9 patients (60%). The 30-day mortality rate was 33%.

A serum lactate level above 2 mmol/L on admission may be associated with an unfavorable prognosis. Early diagnosis, referral, and rapid revascularization are critical for therapeutic success in AMI.