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Updated: Mar 3, 2026

From Constructs to Crystals – Towards Structure Determination of β-barrel Outer Membrane Proteins
Published on: July 4, 2016
Crystallization and biochemical characterization of an archaeal lectin from Methanococcus voltae A3
N Sivaji1, K V Abhinav1, M Vijayan1
1Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Abstract:
A lectin from Methanococcus voltae A3 has been cloned, expressed, purified and characterized. The lectin appears to be specific for complex sugars. The protein crystallized in a tetragonal space group, with around 16 subunits in the asymmetric unit. Sequence comparisons indicate the lectin to have a β-prism I fold, with poor homology to lectins of known three-dimensional structure.
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