Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Concepts of Health and Illness01:29

Concepts of Health and Illness

18.9K
Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
18.9K
Factors Affecting Illness01:18

Factors Affecting Illness

5.5K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
5.5K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

2.0K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
2.0K
Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

1.4K
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
1.4K
Classification of Illness01:17

Classification of Illness

9.1K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
9.1K
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

796
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
796

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kidney outcomes in pure membranous versus proliferative lupus nephritis: A 14-year Latin American cohort study.

Lupus·2026
Same author

Factors associated with changes in self-efficacy in patients with systemic lupus erythematosus. Data from the almenara lupus cohort.

Lupus·2026
Same author

Treatment patterns and outcomes of first lupus nephritis episode over 25 years in two Latin American cohorts.

Lupus·2026
Same author

Prognostic risk score for end-stage kidney disease in Latin American lupus nephritis: Integrating clinical and histological data.

Lupus·2026
Same author

Paraneoplastic necrotizing medium-vessel vasculitis mimicking polyarteritis nodosa with large-vessel involvement.

Clinical rheumatology·2026
Same author

Lupus in Latin America: Where are we now?

Clinical rheumatology·2026

Related Experiment Video

Updated: Mar 3, 2026

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

16.4K

The evolving concept of SLE comorbidities.

Luis Alonso González1, Graciela S Alarcón2

  • 1a Division of Rheumatology, Department of Internal Medicine, School of Medicine , Universidad de Antioquia , Medellín , Colombia.

Expert Review of Clinical Immunology
|May 5, 2017
PubMed
Summary

Systemic lupus erythematosus (SLE) patients face higher risks of cardiovascular disease (CVD), cancer, and osteoporosis. Managing these comorbidities is crucial for improving patient outcomes and survival.

Keywords:
Comorbiditycardiovascular diseasemalignancyosteoporosissystemic lupus erythematosus

More Related Videos

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

9.2K

Related Experiment Videos

Last Updated: Mar 3, 2026

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

16.4K
Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

9.2K

Area of Science:

  • Rheumatology
  • Internal Medicine
  • Public Health

Background:

  • Systemic lupus erythematosus (SLE) survival has improved, increasing comorbidity risks.
  • Cardiovascular disease (CVD), malignancies, and osteoporosis are significant comorbidities in SLE patients.

Purpose of the Study:

  • To review the incidence, prevalence, prevention, and treatment of CVD, malignancies, and osteoporosis in SLE patients.
  • To highlight the importance of managing comorbidities for improved patient outcomes.

Main Methods:

  • Literature search of the PubMed database from January 1976 to December 2016.
  • Inclusion of over 100 full-length articles focusing on SLE comorbidities.
  • Keywords used: 'comorbidities', 'cardiovascular disease', 'osteoporosis', 'malignancy', 'cancer', 'lupus'.

Main Results:

  • SLE patients have an increased risk of developing CVD, malignancies, and osteoporosis.
  • Effective management requires addressing both SLE and its associated comorbidities.
  • Specific strategies include treating SLE patients as coronary artery disease (CAD) equivalents and managing modifiable risk factors.

Conclusions:

  • Therapeutic strategies for SLE must encompass disease remission and comorbidity management.
  • Rigorous management of modifiable cardiovascular risk factors is essential.
  • Addressing osteoporosis and cancer risks through lifestyle modifications and screening is vital for SLE patient care.