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Cardiovascular health in an aging HIV population

Franck Boccara1

  • 1Division of Cardiology, Saint Antoine University Hospital, APHP, INSERM, UMR-S 938, UPMC, Paris, France.

AIDS (London, England)
|May 5, 2017
PubMed

Insights

People living with HIV are aging and facing increased cardiovascular disease (CVD) risks. This review highlights CVD risks in aging HIV populations and effective prevention strategies for those on multiple medications.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Cardiology

Background:

  • Populations with HIV on antiretroviral therapy are aging and experiencing more chronic disease comorbidities.
  • Cardiovascular disease (CVD) is a leading cause of illness and death in people with HIV, mirroring trends in the general population.
  • Increased CVD risk in HIV is linked to physiological aging, hypertension, diabetes, and renal failure.

Purpose of the Study:

  • To review the cardiovascular disease (CVD) risks in the aging HIV-positive population.
  • To focus on atherosclerotic CVD (ASCVD) and heart failure within this demographic.
  • To discuss effective CVD prevention strategies, considering polypharmacy in aging individuals with HIV.

Main Methods:

  • Literature review focusing on aging HIV populations and cardiovascular disease.
  • Analysis of factors contributing to increased CVD incidence in HIV.
  • Examination of prevention strategies for CVD in the context of polypharmacy.

Main Results:

  • Aging HIV population faces significant cardiovascular disease (CVD) risks, including atherosclerotic CVD (ASCVD) and heart failure.
  • HIV may be an independent risk factor for CVD, alongside physiological aging and comorbidities.
  • Polypharmacy in aging individuals with HIV complicates CVD management and prevention.

Conclusions:

  • Cardiovascular disease is a critical concern for the aging HIV population.
  • Further research is needed to clarify HIV's independent role in CVD and its impact on aging.
  • Effective, individualized CVD prevention strategies are essential for aging people with HIV, accounting for polypharmacy.

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