Acute Coronary Stent Thrombosis in Modern Era: Etiology, Treatment, and Prognosis

Area of Science:

• Cardiology
• Interventional Cardiology
• Biomedical Science

Background:

• Acute stent thrombosis (AST) is a rare, life-threatening complication following coronary artery stenting.
• Despite advances in techniques and therapies, AST remains a significant clinical challenge for cardiologists.

Purpose of the Study:

• To provide a comprehensive overview of acute stent thrombosis.
• To discuss the prevalence, risk factors, prognosis, and pathogenesis of AST.
• To identify knowledge gaps and recommend diagnostic and management strategies for AST.

Main Methods:

• This review synthesizes current literature on acute stent thrombosis.
• It examines epidemiological data, etiological factors, and clinical outcomes.
• Diagnostic criteria and therapeutic approaches are critically evaluated.

Main Results:

• AST, though infrequent, carries a high mortality and morbidity rate.
• Multiple factors contribute to AST, including patient-related, stent-related, and procedural elements.
• Current management strategies aim to mitigate risks but require further refinement.

Conclusions:

• Effective management of AST necessitates a thorough understanding of its complex pathophysiology.
• Individualized diagnostic and treatment strategies are crucial for improving patient outcomes.
• Further research is needed to address existing knowledge gaps in AST prevention and treatment.