Related Experiment Video

Updated: Mar 3, 2026

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing
09:44

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing

Published on: December 23, 2022

3.0K

Complete Genome Sequence of the Uropathogenic Escherichia coli Strain NU14

Kurosh S Mehershahi1, Swaine L Chen2,3

  • 1National University of Singapore, Singapore.

Genome Announcements
|May 6, 2017
PubMed

Insights

We sequenced the genome of uropathogenic Escherichia coli strain NU14. This bacterium commonly causes urinary tract infections and pyelonephritis in humans, aiding pathogenesis research.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Escherichia coli is a leading cause of human urinary tract infections (UTIs).
  • Uropathogenic E. coli (UPEC) strains are responsible for significant morbidity.
  • Understanding UPEC pathogenesis is crucial for developing effective treatments.

Purpose of the Study:

  • To present the complete genome sequence of a clinically relevant UPEC strain, NU14.
  • To provide a genomic resource for studying E. coli pathogenesis in pyelonephritis.

Main Methods:

  • Whole-genome sequencing of the clinical isolate E. coli NU14.
  • Bioinformatic analysis of the obtained genome sequence.

Main Results:

  • The complete genome sequence of UPEC strain NU14 was determined.
  • This genomic data provides insights into the genetic makeup of a pyelonephritis-causing E. coli strain.

Conclusions:

  • The genome sequence of E. coli NU14 is now available for research.
  • This resource will facilitate studies on UPEC virulence factors and host-pathogen interactions.

More Related Videos

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies12:08

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies

Published on: August 20, 2021

5.9K
Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

47.1K

Related Concept Videos

Stringent Response in E. coli01:23

Stringent Response in E. coli

Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
421