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[An increase of CDP-choline: diglyceride phosphocholine transferase reaction in microsome fraction and its decrease
Ukrainskii Biokhimicheskii Zhurnal (1978)
|July 1, 1988
Abstract:
The availability of CDP-choline: diaglyceride phosphocholine transpherase activity in the rat liver nuclear membrane fraction is shown. It is established that the enzyme activity in nuclear membrane fraction makes up less than 1/3 of the analogous activity in microsomes. The hydrocortisone treatment of animals leads to an increase of the enzyme activity in microsomes and to a decrease in the nuclear membranes. The obtained data indicate the existence of the own enzyme of phosphatidyl choline synthesis in the nuclear membranes. This enzyme is, probably, responsible for the nuclear membrane structure when the functional status of cell changes.