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Updated: Mar 3, 2026

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Decarboxylative Borylation of Aliphatic Esters under Visible-Light Photoredox Conditions
Dawei Hu1, Linghua Wang1, Pengfei Li1
1Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.
Abstract:
The conventional methods for preparing alkyl boronates often necessitate anhydrous and demanding reaction conditions. Herein, a new, operationally simple decarboxylative borylation reaction of readily available aliphatic acid derivatives under additive-free visible-light photoredox conditions in nonanhydrous solvents has been described. Primary and secondary alkyl boronates or tetrafluoroborates with various functional groups were prepared accordingly. A catalytic cycle involving alkyl radical reaction with base-activated diboron species has been proposed.
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