Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rapidly Varying Flow01:24

Rapidly Varying Flow

561
Rapidly varying flow (RVF) in open channels is characterized by abrupt changes in flow depth over a short distance, with the rate of depth change relative to distance often approaching unity. These flows are inherently complex due to their transient and multi-dimensional nature, making exact analysis difficult. However, approximate solutions using simplified models provide valuable insights into their behavior.Key Features of Rapidly Varying FlowRVF is commonly observed in scenarios involving...
561
Fast Decoupled and DC Powerflow01:24

Fast Decoupled and DC Powerflow

790
The fast decoupled power flow method addresses contingencies in power system operations, such as generator outages or transmission line failures. This method provides quick power flow solutions, essential for real-time system adjustments. Fast decoupled power flow algorithms simplify the Jacobian matrix by neglecting certain elements, leading to two sets of decoupled equations:
790
Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

6.0K
Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
6.0K
Poiseuille's Law and Reynolds Number01:10

Poiseuille's Law and Reynolds Number

9.6K
Any fluid in a horizontal tube can flow due to pressure differences—fluid flows from high to low pressure. The flow rate (Q) is the ratio of pressure difference and resistance through a horizontal tube. The greater the pressure difference, the higher the flow rate. The flow resistance is expressed as:
9.6K
Plane Potential Flows01:23

Plane Potential Flows

1.0K
Plane potential flows simplify fluid motion by assuming the fluid to be irrotational and incompressible. These characteristics allow these flows to be described by a velocity potential function, ϕ, representing the flow speed in a given direction, and a stream function, ψ, that visualizes the flow path, both governed by Laplace's equation. These parameters help in estimating flow patterns, velocity distributions, and pressure fields around various hydraulic structures.
Uniform...
1.0K
The Power Flow Problem and Solution01:26

The Power Flow Problem and Solution

913
Power flow problem analysis is fundamental for determining real and reactive power flows in network components, such as transmission lines, transformers, and loads. The power system's single-line diagram provides data on the bus, transmission line, and transformer. Each bus k in the system is characterized by four key variables: voltage magnitude Vk​, phase angle δk​, real power Pk​, and reactive power Qk​. Two of these four variables are inputs, while the power flow program computes...
913

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Percutaneous Retrieval of Embolized Left Atrial Appendage Occlusion Device From Mitral Valve Apparatus.

JACC. Case reports·2026
Same author

Medical therapies to prevent the development and progression of calcific aortic valve stenosis: a contemporary review.

Expert review of cardiovascular therapy·2026
Same author

Outcomes according to timely or delayed primary percutaneous coronary intervention or fibrinolysis in a national registry of patients with ST-segment elevation myocardial infarction.

Open heart·2026
Same author

Drug-coated balloon angioplasty for coronary and peripheral artery disease: latest evidence and clinical indications.

Nature reviews. Cardiology·2026
Same author

A Prospective, Multicenter, Open Label Study Investigating the Implementation of a Standardized Algorithm for Coronary CaLcificatiOn With PlaquE Modification Using UltraSound Guidance to Improve Procedural and Clinical Outcomes (CYCLOPES): Design and Rationale of the CYCLOPES Trial.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2025
Same author

Drug Coated Balloons Versus Drug-Eluting Stents in Patients With De Novo Coronary Artery Disease.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2025

Related Experiment Video

Updated: Mar 3, 2026

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

8.5K

Fractional flow reserve in 2017: current data and everyday practice.

J J Coughlan1, Colin MacDonnell2, Samer Arnous1

  • 1a Department of Cardiology , University Hospital Limerick , Dooradoyle , Ireland.

Expert Review of Cardiovascular Therapy
|May 6, 2017
PubMed
Summary

Fractional flow reserve (FFR) is a key diagnostic tool in cardiology, guiding decisions for percutaneous coronary intervention (PCI). FFR offers superior outcomes compared to traditional angiography, proving valuable in patient care and cost-effectiveness.

Keywords:
Coronary artery diseaseFractional flow reserveIschemic heart disease

More Related Videos

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

15.8K
In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.9K

Related Experiment Videos

Last Updated: Mar 3, 2026

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

8.5K
Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice
06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

15.8K
In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.9K

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Physiology

Background:

  • Fractional flow reserve (FFR) is an objective physiological index used in coronary angiography.
  • It quantifies blood flow reduction due to coronary artery stenosis, assessing lesion significance.
  • FFR-guided percutaneous coronary intervention (PCI) demonstrates superiority over angiography-guided PCI in clinical trials.

Purpose of the Study:

  • To review the physiological principles of FFR.
  • To discuss landmark clinical trials validating FFR's diagnostic utility.
  • To outline current recommendations and future directions for FFR technology.

Main Methods:

  • Review of physiological principles of FFR.
  • Analysis of landmark clinical trials and registries.
  • Examination of current clinical practice guidelines and future trends.

Main Results:

  • FFR provides functional significance of coronary lesions.
  • FFR-guided PCI is superior to angiography-guided PCI.
  • FFR is potentially cost-effective and essential in modern catheterization labs.

Conclusions:

  • FFR is an essential diagnostic tool for optimizing PCI decisions.
  • It serves as an adjunctive invasive tool, used with clinical assessment.
  • Future trials like FAME3 are expected to further establish FFR's role in risk stratification.