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Updated: Mar 3, 2026
Murine Fetal Echocardiography
Published on: February 15, 2013
Natural history of fetal isolated ventriculomegaly: Comparison between pre- and post-natal imaging
Sharon Perlman1,2, Omer Bar-Yosef2,3, Jeffrey-Michael Jacobson2,4
1a Prenatal Diagnostic Unit, Department of Obstetrics and Gynecology , Sheba Medical Center , Ramat Gan , Israel.
Purpose:
The aim of our study was to assess the agreement between pre- and post-natal measurements in prenatal isolated ventriculomegaly.
Methods:
Ninety-two women were referred for lateral ventricular abnormality and followed prospectively. Cases with at least one dilated lateral ventricle ≥10 mm and a normal work up (serological tests, detailed anatomical scan, fetal brain MR imaging, genetic counseling, and amniocentesis) were considered idiopathic ventriculomegaly and comprised the study group for post-natal follow up. Prenatal measurements were performed by ultrasound and MR imaging. Post-natal measurements were performed by cranial sonography at age of 1-3 months. Measurements were performed in the customary plane for each modality. Paired Student's t test was used to assess the mean difference between pre- and postnatal measurements.
Results:
Forty three cases comprised the study group for post-natal measurements. A statistically significant decrease in ventricular width (p < .001) was observed between pre- and post-natal measurements. On clinical follow up for 24 months, all cases were normal except three who demonstrated very mild neurological deficits.
Conclusions:
Our study indicates statistically significant regression of prenatal isolated ventriculomegaly in the post-natal period.
