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A systems-level model reveals that 1,2-Propanediol utilization microcompartments enhance pathway flux through

Christopher M Jakobson1, Danielle Tullman-Ercek1, Marilyn F Slininger2

  • 1Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA.

Plos Computational Biology
|May 6, 2017
PubMed
Summary

Bacterial microcompartments enhance metabolic flux by creating concentration gradients, primarily by decoupling internal and external metabolite levels. This spatial organization is crucial for efficient carbon source metabolism in bacteria like Salmonella enterica.

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