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Related Experiment Video

Updated: Mar 3, 2026

Expansion and Adipogenesis Induction of Adipocyte Progenitors from Perivascular Adipose Tissue Isolated by Magnetic Activated Cell Sorting
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Do Adipocytes Emerge from Mural Progenitors?

Lavanya Vishvanath1, Jonathan Z Long2, Bruce M Spiegelman2

  • 1Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell Stem Cell
|May 6, 2017
PubMed
Summary
This summary is machine-generated.

Mural cells, crucial for blood vessel health, were found to be adipogenic (fat-producing) in recent studies. This finding contrasts with previous research, sparking debate in the stem cell and vascular biology fields.

Area of Science:

  • Vascular Biology
  • Stem Cell Research
  • Adipogenesis

Background:

  • Mural cells, also known as pericytes, are essential for vascular development and function.

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  • Recent lineage tracing studies have proposed an adipogenic potential for mural cells.
  • This contrasts with established understanding and prior research findings.