Related Experiment Video
Updated: Mar 3, 2026
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Infection with enterotoxigenic Staphylococcus aureus as a concern in patients with gastroenteritis
Masoumeh Azimirad1, Anahita Dezfulian2, Masoud Alebouyeh1
1Foodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Objectives:
Intestinal overgrowth of Staphylococcus aureus may promote unpleasant disorders in the human intestinal tract. This study assessed the prevalence of enterotoxigenic multidrug-resistant S. aureus (MDR-SA) in patients with gastroenteritis.
Methods:
Microbiological analysis of 345 faecal samples from patients with gastroenteritis was performed to detect infection with S. aureus in the absence of common enteric pathogens. Methicillin-resistant S. aureus (MRSA) was characterised by the cefoxitin disk diffusion method. PCR amplification of enterotoxin genes (sea, seb, sec, sed and see) was carried out on all S. aureus strains, and association of resistance patterns with the toxigenicity of strains was determined statistically.
Results:
Infection with S. aureus was detected in 64 samples (18.6%), of which 51 (79.7%) and 41 (64.1%) were determined as MRSA and MDR-SA, respectively. Resistance to six antibiotic classes was the most common MDR pattern (48.8%; 20/41). In total, 50% of the strains (32/64) carried the studied enterotoxin genes; the most common was sea (56.1%), followed by sec (4.9%) and see (4.9%). These genes were more prevalent among MDR-MRSA (58.8%) compared with methicillin-sensitive S. aureus (15.4%) strains.
Conclusions:
These results confirmed the involvement of enterotoxigenic MRSA in the occurrence of gastroenteritis.
More Related Videos
Related Concept Videos
01:17Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
01:25Endocarditis I: Introduction