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Related Experiment Video

Updated: Mar 2, 2026

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

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Published on: May 7, 2014

Normal Aging Slows Spontaneous Switching in Auditory and Visual Bistability.

Hirohito M Kondo¹, Takanori Kochiyama²

¹School of Psychology, Chukyo University, Nagoya, Aichi 466-8666, Japan; Human Information Science Laboratory, NTT Communication Science Laboratories, NTT Corporation, Atsugi, Kanagawa 243-0198, Japan.

|May 9, 2017

Summary

Aging reduces perceptual switches in auditory and visual tasks. Higher GABA levels in sensory areas correlate with better volitional control, suggesting neurochemical factors influence age-related perceptual changes.

Keywords:

MRS age attention awareness perceptual organization scene analysis

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Area of Science:

Neuroscience
Cognitive Psychology
Sensory Perception

Background:

Age-related sensory changes impact quality of life.
Perceptual organization's response to aging is debated.
Neurochemical underpinnings of age-related perceptual shifts require investigation.

Purpose of the Study:

Investigate age effects on auditory and visual bistability.
Examine the neurochemical basis, specifically GABA, of age-related perceptual control.
Determine the relationship between GABA concentration and volitional control in sensory processing.

Main Methods:

Utilized auditory streaming and visual plaid tasks to assess perceptual bistability.
Measured perceptual switch frequency in young and middle-aged adults (20-60 years).
Employed magnetic resonance spectroscopy to quantify brain GABA levels in relevant regions.

Main Results:

Perceptual switch frequency decreased with advancing age.
Effective volitional control positively correlated with GABA in modality-specific sensory areas.
No correlation observed between GABA and control in prefrontal or anterior cingulate cortices.
Volitional control significantly reduced in older participants.

Conclusions:

Age-related and neurochemical factors influence sequential scene analysis.
GABAergic system plays a role in maintaining perceptual control with age.
Sensory-specific brain regions are critical for age-related modulation of perceptual stability.