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Coffee and autoimmunity: More than a mere hot beverage!
Kassem Sharif1, Abdulla Watad1, Nicola Luigi Bragazzi2
1Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Israel; Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Autoimmunity Reviews
|May 9, 2017
Summary
Coffee intake
Area of Science:
- Immunology and Nutritional Science
Background:
- Coffee is a widely consumed beverage with documented health impacts.
- Research increasingly explores coffee's influence on chronic diseases and the immune system.
Purpose of the Study:
- To review the association between coffee consumption and autoimmune diseases.
- To investigate coffee's impact on immune function and disease management.
Main Methods:
- Systematic literature review of existing studies on coffee intake and autoimmune diseases.
- Analysis of data regarding coffee's influence on disease risk, progression, and treatment efficacy.
Main Results:
- Coffee consumption may increase rheumatoid arthritis (RA) and type 1 diabetes mellitus (T1DM) risk.
- Coffee may offer protection against multiple sclerosis, primary sclerosing cholangitis, and ulcerative colitis.
- Conflicting or no significant associations were found for other autoimmune diseases; impacts on treatment efficacy were noted.
Conclusions:
- Coffee's relationship with autoimmune diseases is complex, with varied effects on risk and progression.
- Further research is needed for several autoimmune conditions where data is currently lacking.
- Coffee intake can influence the management and efficacy of treatments for certain autoimmune conditions.
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