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The CYP2D6 Animal Model: How to Induce Autoimmune Hepatitis in Mice
Published on: February 3, 2012
Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
Wonyong Jo1, Young-Sun Suh1, Sang-Il Lee1
1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea.
Abstract:
We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case confirms the need to consider AIH in psoriasis patients who experience new elevations in liver enzymes. To our knowledge, this is first description of the development of AIH in an immunosuppressant-naïve patient with psoriasis.
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