The origin of Metazoa: a unicellular perspective
Arnau Sebé-Pedrós1, Bernard M Degnan2, Iñaki Ruiz-Trillo3,4,5
1Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Herzl Street 234, Rehovot 7610001, Israel.
Abstract:
The first animals evolved from an unknown single-celled ancestor in the Precambrian period. Recently, the identification and characterization of the genomic and cellular traits of the protists most closely related to animals have shed light on the origin of animals. Comparisons of animals with these unicellular relatives allow us to reconstruct the first evolutionary steps towards animal multicellularity. Here, we review the results of these investigations and discuss their implications for understanding the earliest stages of animal evolution, including the origin of metazoan genes and genome function.
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